HomozygosityMapper--an interactive approach to homozygosity mapping

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HomozygosityMapper—an interactive approach to homozygosity mapping

Homozygosity mapping is a common method for mapping recessive traits in consanguineous families. In most studies, applications for multipoint linkage analyses are applied to determine the genomic region linked to the disease. Unfortunately, these are neither suited for very large families nor for the inclusion of tens of thousands of SNPs. Even if less than 10,000 markers are employed, such an ...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2009

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/gkp369